Autophagy plays a critical role in the physiology and pathophysiology of hepatocytes.High level of homocysteine (Hcy) promotes autophagy in hepatocytes, but the underlying mechanism is still unknown.Here, we investigate the relationship between Hcy-induced autophagy level and the expression of nuclear transcription factor EB (TFEB).The results show
African Biscuit Board tropical forests of the equatorial belt might receive significant input of extra nitrogen derived from biomass burning occurring in the north savanna belt and transported equatorward by northeastern winds.In order to test this hypothesis an experiment was set up in a tropical rain forest in the Ankasa Game Reserve and Nini-Suh
Although structurally and biochemically similar to the cellular prion (PrP(C)), doppel (Dpl) is unique in its biological functions.There are no reports about any neurodegenerative diseases induced by Dpl.However the artificial expression of Dpl in the PrP-deficient mouse brain causes ataxia with Purkinje cell death.Abundant Dpl proteins have been f
Faced with the energy development situation in the new epoch, it is key measures for promoting the development of power energy Internet to effectively integrate the information of power users, grid companies and suppliers, and to comprehensively analyze the source network load and storage characteristics.Therefore, it is crucial to simulate the typ
This article recognizes the centrality of the June 2013 Manifestations as a turning point for the opening of the crisis of the democratic-representative model still experienced today.It argues that from that month of June a critical social environment was created for this political system, pointing to the need to readjust the political practices of